Iopamidol

Mechanism of Action
Radiographic visualization achieved through the opacification of vessels and anatomical structures in the path of flow of the contrast media 
Pharmacokinetics
Excretion: Urine (80-90%)
Contraindications
• Hypersensitivity to product or components
• Intrathecal injection
• Significant bacterial infection
Adverse Reactions
Hot flashes, Angina pectoris, Flushing, Bradycardia, Hypotension, Hives
Major Drug Interactions
-
Warnings
• Not for intrathecal use
Recommendations for Patient
• Before examination patients should be well hydrated to prevent contrast associated nephropathy
Pregnancy Considerations
Category: B
Breastfeeding Considerations
Intravenous iodinated contrast media are poorly excreted into breastmilk and poorly absorbed orally so they are not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants.

Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: Maybe acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.