Mechanism of Action
Parenteral dextrose is oxidized to carbon dioxide and water, and provides 3.4 cal/g of d-glucose
Pharmacokinetics
Onset of action: 10 min
Contraindications
• Documented hypersensitivity
• Severe dehydration
Adverse Reactions
-
Major Drug Interactions
-
Warnings
• Use caution in DM or carbohydrate intolerance
Recommendations for Patient
-
Pregnancy Considerations
Category: C
Breastfeeding Considerations
Excretion in milk unknown, use with caution
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: Maybe acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
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